Vanderbilt VICB Chemical Synthesis Core

Overview of Services

The Chemical Synthesis Core was established within the Vanderbilt Institute of Chemical Biology to support the organic and medicinal chemistry needs of Vanderbilt investigators.

The primary focus of the core is to facilitate biology-oriented projects within the medical center and the university by assisting with the chemistry aspect of the project. The core works independently or in collaboration with the VICB High Throughput Screening Center on the synthesis of literature-cited compounds (including patented ones) as well as full scale lead optimization of a compound.

The Core supports the Vanderbilt community in all aspects of medicinal and organic synthesis. We provide quantities of known or unknown compounds with an emphasis on parallel synthesis of small libraries, HPLC purification, and scale-up of synthetic procedures. Services include:
• Custom synthesis of compounds
• Synthesis and design of small molecule probes
• Dye synthesis
• Prostaglandin synthesis
• Compound libraries
• Medicinal chemistry
• Large-scale synthesis (up to 100g)
• HPLC purification capabilities
• Analytical support (NMR, MS)

Leadership

Christov,Plamen P Drug Discovery Scientist II
Brendan Dutter Staff Scientist
Guttentag, Ben Research Asst I, Core
Jana,Somnath Drug Discovery Scientist I
Lamers,Alexander  Research Asst III, Core
Romaine,Ian M Drug Discovery Scientist I
Tian,Jianhua Drug Discovery Scientist I
Kim,Kwangho Research Asst Professor
Sulikowski, Gary Professor

Location and hours of operation

Hours  

Monday - Friday 
 8AM-4PM

 

Links and Resources

  1. https://medschool.vanderbilt.edu/syncore/

Contacts

Name Role Phone Email Location
Kwangho Kim
Assistant director
 
615-322-8035
 
kwangho.kim@vanderbilt.edu
 

 
Plamen
Manager
 
615-322-6072
 
plamen.p.christov@vanderbilt.edu
 

 

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